There was in reality, no truly efficient oral medication for erectile dysfunction or impotence. Most of the useful drugs that were available in the market had to be inserted into the urethra or injected into the penis. But with the constant spirit of research and innovation, today the treatment of erectile dysfunction is much easier. It is all possible because of a class of drugs called phosphodiesterase-5 (PDE-5) inhibitors. The wonderful medication tadalafil (Cialis) is today claiming a sure shot improvement in erectile function.

The main function of Cialis is to prevent the breakdown of nitric oxide, a chemical messenger that promotes relaxation and opening of the blood vessels that supply erectile tissue in the penis. These vessels expand under the influence of nitric oxide and stay dilated because of which there is an increased blood flow which makes erectile tissue swell and compress the veins that carry blood out of the penis, resulting in a full erection. Generally the PDE-5 inhibitors do not automatically trigger erections. To start the whole process, sexual stimulation also is also needed. The wonder drug Cialis enables a more complete response to sexual stimulation.

Today with the explosion of information technology, this wonder drug Cialis is available on thousands of virtual shops present on internet. One can easily buy Cialis from any online American or European pharmacy. But there is also an another side of the whole issue and that is the safety aspect of consuming this drug. Though this wonder drug can help many people but still not all men can safely take them.

Majority of the scientists and doctors are of the view that PDE-5 inhibitors may worsen certain medical conditions and interact with a number of drugs. Therefore, erectile dysfunction medications are dangerous when used with nitrate medications, such as nitroglycerin, often prescribed to prevent or treat acute angina (chest pain due to coronary artery disease).

Today a plethora of clinical trials have shown that PDE-5 inhibitors improve erectile function regardless of the underlying cause or causes and the fact has been very well established that Cialis increase the number and quality of erections and sexual experiences in men with erectile dysfunction due to arteriosclerosis, spinal cord injury, diabetes, aftereffects of prostate cancer surgery or the depression.